Clinical Lab Partnership Program Provides Ready Supplies and Reliable Support for COVID-19 Testing The UK Minister said considering the emergence of thousands of variants,... Denmark Finance Minister revealed that the introduction of these digital... One of the detained women was forced to take off her bra and undress to... A total of 81 people were fined for violating the curfew and three people... BGI Group sold millions of COVID-19 test kits outside China, International Business Times, Singapore Edition, Where is BullHorn Lady? [54] It was done on 2,200 samples mostly from the United States,[46] out of which 1,600 were of individuals who participated in the Study of Mathematically Precocious Youth and reportedly have IQs over 160, collected by American psychologist and geneticist Robert Plomin. BGI Genomics, its main channel for commercialization, is a leading gene sequencing provider in China and went public in 2017. The sea slug uses genes from the algae to synthesize chlorophyll, the first interspecies of gene transfer discovered. And he says BGI, which manufactures sequencing equipment, sells diagnostic tests, and performs research for drug companies, can be the company to take it there, becoming China… [92][93] In response, BGI has filed patent infringement lawsuits against Illumina alleging violations of federal antitrust and California unfair competition laws. Sequenced the first diploid genome of an Asian individual, Initiated building a sequence map of the human, The BGI's first project was contributing 1% of the, Contributed 10% of sequence information for the, Produced proof-of-principle study for sequencing the, First Chinese institution to sequence the, Key player in the open source data release and analysis of the, Key player in the Sino-British Chicken Genome Project. [20] That year they also launched their own scientific journal, GigaScience,[21] partnering with BioMed Central to publish data-heavy life science papers. [20], An international project launched in 1990 and declared complete in 2003. [14] In 2010, BGI Americas was established with its main office in Cambridge, Massachusetts, USA, and BGI Europe was established in Copenhagen, Denmark. The US security officials have warned labs against the use of Chinese test kits. American physicist Stephen Hsu joined as a scientific adviser and was one of the project's leaders. [88] Despite being the 5th test to be given WHO Emergency Use Listing,[89] and getting top marks in sensitivity tests in a Dutch study independently validating commercially available tests. [90] BGI Genomics defended the product, blaming differences in thresholds used between labs looking at very low levels of the virus. [53], A project called the Cognitive Genomics project focused on the research of the genetic basis of intelligence was announced in August 2012. [4] In May 2018, was reached an agreement with Mount Sinai Hospital (Toronto), Canada, for first installation of BGISEQ platforms in North America. [65] The project aim was to significantly advance conservation research and was auspiciously announced for the Chinese year of the Tiger. "One researcher, Peng Shaoliang, was instrumental in developing software to speed up BGI's sequencing of human genomes using supercomputing developed by NUDT," reported Reuters. BGI also stated that it uses the supercomputer located in the National Supercomputer Center in Guangzhou on a commercial basis and other supercomputing platforms to speed up the research process. [19] Since 2012, it has started to commercialize its services, having investments from China Life Insurance Company, Citic's Goldstone Investment, Jack Ma's Yunfeng Capital, and SoftBank China Capital. BGI Group, based in Shenzhen, has grown quickly by selling genetic sequencing services to universities and health systems around the world and amassing a large DNA databank. Population genomics is the analysis of polymorphic DNA, which is essential to understand how the patterns of genetic variation in organisms have been shaped by different evolutionary forces, such as mutation, natural selection, genetic drift, population structure, and population size change. Sequencing their genomes could elucidate the mechanism of that transfer. [13][59] In 2018 it was announced that the 1KP project was being succeeded by the 10KP project to sequence 10,000 plant species to a high (chromosome level) quality. "BGI Group, the world’s largest genomics company, has worked with China’s military on research that ranges from mass testing for respiratory pathogens to brain science, a Reuters review of research, patent filings and other documents has found. ", "China's genomics company BGI makes stock market debut", "The sequence and de novo assembly of the giant panda genome", "De novo assembly of human genomes with massively parallel short read sequencing", "Ancient human genome sequence of an extinct Palaeo-Eskimo", "The diploid genome sequence of an Asian individual", "To Start Building 'Human Pan-Genome,' BGI De Novo Assembles Two Genomes from Illumina Data | In Sequence | Sequencing | GenomeWeb", "BGI – China's Genomics Center Has A Hand in Everything", "A human gut microbial gene catalogue established by metagenomic sequencing", "International Team Catalogs Microbial Genes in the Human Gut | GenomeWeb Daily News | Sequencing | GenomeWeb", German Teams, BGI and Life Technologies Identify Deadly European E.coli Strain, "Complete Resequencing of 40 Genomes Reveals Domestication Events and Genes in Silkworm (Bombyx)", "Chinese bioscience: The sequence factory", "The genome of the cucumber, Cucumis sativus L", "2016 tables: Institutions - corporate (China)", "2016 tables: Institutions - corporate (Global)", "Collaboration surges as businesses outsource discovery to academia", "Following the giant's paces-governance issues and bioethical reflections in China", "Breaking News: BGI Launches Two Important Global Plans at JP Morgan Healthcare Conference", "Chinese scientists sequence 1st volunteer's genome", "BGI Offers Next-Gen Sequencing Service, Kicks Off 100-Genome Sequencing Project | In Sequence | Sequencing | GenomeWeb", TuanHuang - The First Asian Diploid Genome, "BGI Announces New Partnerships and 8th Anniversary Milestone in US", "Chinese project probes the genetics of genius", "China's BGI to Sequence 2,200 Geniuses In Search For "Smart" Genes", "Second-generation PLINK: rising to the challenge of larger and richer datasets", "One thousand plant transcriptomes and the phylogenomics of green plants", "BGI Seeks Proposals to Sequence 1,000 Plant, Animal Genomes; Pledges $100M Toward Effort", "10KP: A phylodiverse genome sequencing plan", "Genome projects launched for three extreme-environment animals", "Draft genome sequence of the Tibetan antelope", "Population Genomics Reveal Recent Speciation and Rapid Evolutionary Adaptation in Polar Bears", "Two Antarctic penguin genomes reveal insights into their evolutionary history and molecular changes related to the Antarctic environment", "BGI to Sequence Tiger, Lion, and Leopard Species This Year | In Sequence | Sequencing | GenomeWeb", "The tiger genome and comparative analysis with lion and snow leopard genomes", A draft genome assembly of the solar-powered sea slug Elysia chlorotica. But can it compete in the U.S.? In an interview, Rev. [7][8] After the project was completed, funding dried up, after which BGI moved to Hangzhou in exchange for funding from the Hangzhou Municipal Government. BGI | Complete Birks Group Inc. stock news by MarketWatch. They are reportedly being involved as a sequencing institution in China's US$9.2-billion research project for medical care which will last for 15 years. [73] The BGISEQ-500 was developed as a sequencing platform capable of competing with Illumina's platforms with its quality and reduced price. [6] The Shenzhen company says the low cost will be possible with an "extreme" DNA sequencing system it plans to offer that is capable of decoding the genomes of 100,000 people a year. The Reuters report pointed out a research paper which was authored by BGI founders Yang Huanming and Wang Jian in collaboration with PLA's Key Laboratory of High-Altitude Medicine and the Third Military Medical University. [79][80][81][82][83] In July 2020, it was reported that BGI returned a Paycheck Protection Program loan following media scrutiny. [91], In 2019, competitor Illumina, Inc. filed multiple patent infringement lawsuits against BGI. [84] The same month, the United States Department of Commerce's Bureau of Industry and Security placed two BGI subsidiaries on its Entity List for assisting in alleged human rights abuses due to its genetic analysis work in Xinjiang. A 2018 study by the PLA lab said: "High altitude disease is the main reason for reduced combat effectiveness and health damage to soldiers at high altitudes and influences the results of war." [5][19] In the same year, the BGI was roughly valued at $820 million. However, in a statement, the company told Reuters that it follows international standards and Chinese laws related to open science, data sharing and genomic research. In this particular research, experts looked at the effects of rapid ascent to high altitude on the bodies of "young, healthy men.". [46], An international project launched in 2002 and declared complete in 2009. In January 2018, BGI Genomics CEO, Yin Ye, stated they sequenced over 10,000 WGS samples, with additional 20,000 being sequenced by their BGISEQ-500 platform, about 70% of animals and plants until now were sequenced by the company and their partners, as well worked on "over 10 million clinical samples, including running 2.8 million noninvasive prenatal tests, 2.6 million human papillomavirus tests, 1.53 million hearing impairment tests, just over half a million newborn screening tests, and around 25,000 rare disease tests". For the biopharma industry investment, business development and competitive intelligence professionals who require information to support financing, partnering and licensing activities, BCIQ provides accurate information and context to support profitable and strategic decision making. Yu Jun left BGI at this time purportedly selling his stake to the other 3 founders for a nominal sum. doi:10.1038/sdata.2019.22, "BGI Uses New Short-Read Algorithm to Assemble Panda Genome as Proof of Concept for Human Genome | BioInform | Informatics | GenomeWeb", "BGI Retools Complete Genomics Technology for Its New High-Throughput Benchtop Sequencer", "BGI Launches New Desktop Sequencer in China, Registers Larger Version With CFDA", "BGI Launches Desktop Sequencer in China; Plans to Register Platform With CFDA", "China National GeneBank Opens With Investments From BGI, Government", "BGI Launches New Sequencer as Customers Report Data From Earlier Instruments", "BGI's MGI Tech Launches Two New NGS Platforms", "MGI Introduces Groundbreaking Ultra-High-Throughput Sequencer, MGISEQ-T7", "BGI officially enters Urumqi High-tech Zone", "China expands DNA data grab in troubled western region", "China Uses DNA to Map Faces, With Help From the West", "Chinese coronavirus test maker agreed to build a Xinjiang gene bank", "Chinese biotech giant's U.S. subsidiary returns PPP loan after Axios story", "U.S. blacklists Chinese companies tied to Xinjiang gene bank project", "Commerce Department Adds Eleven Chinese Entities Implicated in Human Rights Abuses in Xinjiang to the Entity List", "China's genetics company BGI denies human rights violations of Uighurs", "Thousands of Swedes got false positive COVID-19 result due to test kit fault", "WHO Emergency Use Listing for In vitro diagnostics (IVDs) Detecting SARS-CoV-2", "Chinese Covid-19 test kit outstrips alternatives in Dutch study", "China's BGI defends COVID-19 test kit after Swedish criticism", "China's BGI gets Australian foothold through mass coronavirus test delivery", "Illumina Nears Win In Bid To Block BGI's DNA Product Sales", "BGI Sues Illumina for Antitrust Violation, Claims Firm Obtained Sequencing Patents Through Fraud", "China gene firm providing worldwide COVID tests worked with Chinese military", https://en.wikipedia.org/w/index.php?title=BGI_Group&oldid=1004333786, Biotechnology companies established in 1999, Genetics or genomics research institutions, Articles with a promotional tone from February 2020, Articles containing potentially dated statements from 2010, All articles containing potentially dated statements, Beijing articles missing geocoordinate data, Wikipedia articles with SUDOC identifiers, Wikipedia articles with WORLDCATID identifiers, Creative Commons Attribution-ShareAlike License, DNBseq™ Platform (next-generation sequencing platform), The NIFTY® Test (a non-invasive prenatal test), Sequenced the first ancient human's genome from the roughly 4,000-year-old permafrost-preserved hair of an extinct. [94], In January 2021, Reuters reported that BGI has worked with the People's Liberation Army and affiliated institutions such as the National University of Defense Technology on efforts to enhance soldiers' strength and other projects. National University of Defence Technology. The three selected genomes are those of two polar animals: the polar bear and emperor penguin, and one altiplano animal: the Tibetan antelope. The analysis of the documents revealed BGI's links to the PLA that included research with the country's top military supercomputing experts. [4] In October 2017, MGI Tech, a subsidiary of BGI, launched two new sequencers MGISEQ-2000 and MGISEQ-200 (later renamed as DNBSEQ-G400 and DNBSEQ-G50),[77] while a year later DNBSEQ-T7. But it added that the documents showed a much deeper link between BGI and the Chinese military than what was known. [17][18], In 2011 BGI reported it employed 4,000 scientists and technicians,[2] and had a $192 million in revenue. BGI Group is the largest biotech company in the world. [46] With it were discovered genes and mutations associated with rare diseases, which was reported in more than 20 scientific publications. [26], The BGI Group subsidiary, BGI Genomics, had made initial public offering in July 2017 at Shenzhen Stock Exchange, raising ¥547 million ($80.7 million), with company's first-day valuation set at over $1.15 billion. [70], In 2010, the institute 500-node supercomputer processed 10 terabytes of raw sequencing data every 24 hours from its current 30 or so Genome Analyzers from Illumina. Seven years ago, BGI began its bid to turn China into a DNA superpower by buying 128 of the world’s fastest sequencing machines---then the Illumina HiSeq 200. [24] That year it bought Complete Genomics of Mountain View, California, a major supplier of DNA sequencing technology, for US$118 million. The Group consists of divisions including BGI Genomics, which focuses on diagnostic tests and services, and MGI, which develops and manufactures advanced equipment such as sequencers, lab automation robots, and imaging. bgi group: China gene firm providing worldwide COVID tests worked with Chinese military Newzpick. They again collaborated in 2017 when CHOP's Children's Brain Tumor Tissue Consortium was joined by BGI's China National GeneBank. It is done in collaboration with many institutes, universities and enterprises, including Biotechnology Research Institute of the Chinese Academy of Agricultural Sciences and the Tianjin Institute of Industrial Biotechnology of Chinese Academy of Sciences. [72][73] In October 2015, BGI launched BGISEQ-500,[74] a larger desktop sequencing system, which received an approved registration as a medical device a year later by the CFDA. Sci Data 6, 190022 (2019). BELGRADE, April 8 (Xinhua) -- China's biotech company BGI group will open two COVID-19 testing labs in Serbia to help fight the COVID-19 pandemic, according to an agreement it signed with the Serbian government Wednesday. It includes sequencing industrial, agricultural, medical microorganism and many others. But BGI has denied such allegations. Nebraska Priest Draws Flak for Performing Exorcism Inside Capitol. The reported market value for BGI Genomics in July 2018 was around $5 billion, as is of another subsidiary, MGI Tech, specialized in developing and manufacturing technology, which IPO of a stake of about 20% for $1 billion is scheduled for 2019 in Hong Kong. [60], In 2009 BGI-Shenzhen announced the launch of three genome projects that focus on animals living in extreme environments. [5] BGI did the genome sequencing for the deadly 2011 Germany E. coli O104:H4 outbreak in three days and released it under an open license. This, along with other COVID testing offers by BGI, so worried Bill Evanina, then the country’s top counterintelligence officer, that he … It created China… In 2010, BGI received a $1.5 billion loan from the state-run China Development Bank, some of which it used to buy 128 sequencing machines from an American firm, San Diego-based Illumina Inc. View real-time stock prices and stock quotes for a full financial overview. They provided 10% of the workload. The final results were published in Nature in 2019. In 2010, the company created China's first cloned pig. [57], Named the 1000 Plant Genomes Project (1KP), this was an international project launched in 2008 and declared complete in 2015. [46], An international project launched in 2008. The company has morphed from a research institute that decoded the DNA of pandas and rice plants into a company active in animal cloning, health testing, and contract research. [5] In 2008, BGI-Shenzhen was officially recognized as a non-profit organization by the Shenzhen government. BGI Park, No.21 Hongan 3rd Street, Yantian District, Shenzhen 518083, China . Built for the Illumina sequencers' short reads, SOAPdenovo has been used to assemble multiple human genomes[29][30][31] (identifying an eight kilobase insertion not detected by mapping to the human reference genome[71]) and animals, like the giant panda. Reuters also revealed that four BGI researchers have been found to be affiliated with another military organization in China, the National University of Defence Technology (NUDT), which is on the US blacklist. "BGI strongly rejects any accusations about links with the PLA, particularly in relation to our COVID-19 test kits," it added. BGI Genomics Co., Ltd. is a holding company that engages in development of science and technology services in genomics field. [46], An international projected jointly initiated with Children's Hospital of Philadelphia in 2011. [4][25] In May 2017, was announced formation of West Coast Innovation Center, co-located in Seattle and San Jose, on the first location planned to work on precision medicine and feature collaborations with University of Washington, the Allen Institute for Brain Science, the Bill & Melinda Gates Foundation, and Washington State University, while on the second's already existing laboratory with 100 employees to develop the next-generation sequencing technologies. The Watson Institute was intended to become a major center for research and education in East Asia modeled after the Cold Spring Harbor Laboratory in the US. BGI, China’s leading genetics company, enlisted a foundation tied to a former U.S. president and used a company linked to the United Arab Emirates’ top spy to promote its efforts. [50][51] The first genome data was published in October 2007. BGI's Wang was involved in another study from 2017 that was published in collaboration with a PLA research center in Xinjiang. In 2007 BGI's headquarters relocated to Shenzhen as "the first citizen-managed, non-profit research institution in China". [72] In November 2016, BGI launched BGISEQ-50, a miniature version of desktop sequencer. Since China has the world's longest highland border, the purpose of such studies can be understood. She added that the world's largest biotech firm's deep ties with the Chinese military was a "reasonable concern to raise" for US officials. Sergey Maximishin Dies Suddenly, Raising Questions, Will Confront Beijing on All Fronts: Biden Says China is Principal Foe. But intelligence officials in the US issued warnings not to share health data with BGI. According to Reuters, the scientist is listed as affiliated with the PLA's Academy of Military Medical Science. [54][55] Other than publishing a new improved version of the popular Genome Wide Association Study tool PLINK,[56] the project was never completed and the lead researchers moved to the US to set up the company Genomic Prediction which provides advanced genetic testing for IVF. In 2002, BGI sequenced the rice genome, which was a cover story in the journal Science. [78], In 2019, it was reported that a BGI subsidiary, Forensic Genomics International, had created a WeChat-enabled database of genetic profiles of people across the country. Apr.28 -- Xu Xun, chief executive officer of BGI Group, discusses the Chinese medical technology firm's strategy to fight the Covid-19. EXPOSED: BGI Group Providing Worldwide COVID-19 Tests A Front For Chinese Military January 30, 2021 BGI Group, the world’s largest genomics company which provided COVID-19 tests worldwide including India, has been exposed as a front for the Chinese military. [1][27] In 2018, the BGI was reportedly 85.3% owned by Wang Jian, and the group owns 42.4% of its main unit BGI Genomics. [33], SOAPdenovo is part of "Short Oligonucleotide Analysis Package" (SOAP), a suite of tools developed by BGI for de novo assembly of human-sized genomes, alignment, SNP detection, resequencing, indel finding, and structural variation analysis. But according to a newly published report, it was found that the Shenzhen-based firm has deep ties to the People's Liberation Army (PLA) and that became a concern of the US intelligence officials. Reuters reported that in terms of the US suspicion, the reviewed documents are neither contradictory nor supportive. As COVID rates and the need for tests were spiking, BGI Group, the world's largest biotech firm - a global giant based in China - approached the state of Washington with an enticing offer. NUDT runs under the supervision of the Central Military Commission, the top-level body that directs the Chinese military and is headed by Xi Jinping. But BGI said Chen had no connection to the academy since 2012. [85][86] BGI responded to the listing stating they "do not condone and would never be involved in any human-rights abuses" and stating that they were puzzled by the decision as the "subsidiary mentioned was established in November 2016 and has not carried out actual business"[87], On August 25, 2020, Reuters reported that about 3,700 people in Sweden were told in error that they had the coronavirus due to a fault in a COVID-19 testing kit from BGI Genomics. They joined in 1999 and provided 1% of the workload. It was blacklisted because the US considers NUDT as a national threat due to the Tianhe-2 supercomputer, which is one of the world's most powerful computers and is used to simulate nuclear explosions. 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[ 46 ], An international project launched in 2008, BGI-Shenzhen was officially recognized as a research... Around 250 papers published in first-class academic journals edited on 2 February,! His stake to the Academy since 2012 was last edited on 2 February 2021 at! Jun left BGI at this time purportedly selling his stake to the Academy since 2012....